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diarrheal diseases, the disease is a common disease worldwide, especially in children, diarrhea, high morbidity in all positions. Recently, the Chinese Medical Association, Department of Paediatric Gastroenterology, Boffo – was General health effects (Tianjin) Pharmacy Ltd. “Children’s Diarrhoeal Disease Research and clinical treatment progress” to continue the project Education Video with the pediatrician said that because of the high incidence of risk major accidents, the children become infected with diarrhea, digestive system, and priorities for children, a critical scientific and rational control. Fuzhou General Hospital of Nanjing Military Region of Pediatrics, said Professor Liyan you that currently, developing countries, diarrheal diseases, the disease is still less than five significant cause of morbidity and mortality. World Health Organization (WHO) statistics for the last few years, the incidence in different age groups each year about 1.5 million passengers, the number of deaths around 150 to 250 million, after the liberation of the Chinese economy and health care improved considerably, but in 1988 the Ministry of Health immunization of 21 provinces and cities, organized by the household survey estimates, China is still 836 million people each year of diarrhea in children under 5 years, of which about 298 million passengers, an average of 2.5 times per year / per person. 1992 Ministry of Health commissioned national experts developed a “diagnosis and treatment of diarrhea in China program.” Implementation of the program in the country, improve diagnosis and treatment of diarrhea and reduce diarrheal diseases disease mortality had an important role, but the treatment of diarrhea, it is still unreasonable application of antibacterial drugs, and excessive IV fluids, and other things. To further standardize treatment of diarrhea in children, while the Medical Group, gastroenterology, infectious group and others developed the “diagnosis and treatment of diarrhea in children principles of expert consensus,” which was recently. Consensus emphasized early childhood diarrhea and oral rehydration, the recommended application of hypotonic oral rehydration salts (ORS hypotonic), zinc, rational use of antimicrobial drugs, preventive vaccines and other key issues. You can replace the standard hypotonic ORS ORSProfessor Liyan Ye consensus on the interpretation of the center explained that the acute diarrhea and dehydration with ORS as diarrhea, 20′s, one of the greatest advances in the field. Standard ORS recommended by WHO in 1971 began the first application. So far, the formula in the world to combat diarrheal diseases, dehydration, diarrhea, regardless of etiology, age, and shown to be effective, and no significant side effects. Since the application of ORS is the last century, in approximately 90 global annual loss of 1 million cases of diarrhea deaths. Of these, a fluid 90% of acute diarrheal diseases, dehydration in children can be used to correct dehydration 95% success. China’s Ministry of Health in 1981, began the initiative to promote the application of ORS. Standard ORS in acute diarrhea and dehydration, but a very good effect, but can not reduce the diarrhea, loose stools, diarrhea frequency and duration of diarrhea. Therefore, nearly 20 years conducted many “improved ORS ‘research. “One way is to reduce the liquid sodium and glucose levels, reduced osmolarity ORS solution to avoid side effects, hypertonic fluids.” Professor Ye Liyan mentioned, in 2001, held in New York to provide the technical meeting, comment Improved ORS Research, WHO, International Children’s Fund (UNICEF) and USAID (USAID) was revised in 2005, “diarrhea treatment recommendation” recommended the use of hypotonic ORS (sodium is reduced to 75 mmol / l glucose decreased by 75 mmol / l, decreased total osmolality to 245 mmol / L), acute non-cholera diarrhea in children, effective and safe. The cumulative loss for the period increased permeability of the excretion of faeces less than the standard ORS group, 36%, vomiting on average 16 times the low permeability of the group, was the standard ORS group 32, hypotonic oral rehydration failure group (patients, use of intravenous fluids) 33 % discount. Hypotonic ORS group hydration treatment group after 24 hours, the mean serum sodium significantly lower than the standard ORS group, and did not make the first hyponatremia or hyponatremia increased, the two groups is similar to that in the urine. Professor Liyan You emphasized that these results indicate that hypotonic ORS is not only safe and effective, rehydration for acute diarrhea in children, it is good. Zinc therapy as soon as possible Build zinc has more than 200 parts enzyme metal, is an immune system development and function of regulation play an important role in the maintenance, but also to improve the interaction between the body’s antioxidants, to improve the overall fight against oxidation. Zinc intestinal structure and function plays an important role for children, zinc deficiency can lead to intestinal villous atrophy, decreased activity of intestinal disaccharidase. Zinc can accelerate recovery of intestinal mucosa, increased levels of enzymes in the brush border. Professor Liyan Ye stressed: “zinc diarrhea considered to affect the immune system, structure or function of the small intestine, diarrhea, epithelial healing.”

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